What symptom is most likely associated with children infected with N. meningitides?

The symptom associated with children infected with Neisseria meningitidis is a cherry-red spot or a purplish rash, known as petechiae or purpura. This rash is significant because it can indicate the presence of meningococcemia, a serious and potentially life-threatening condition caused by the bacteria. In this context, the rash typically appears due to petechial hemorrhages in the skin as a result of the bacteria's impact on the blood vessels, leading to loss of blood and resulting in discoloration of the skin.

This symptom is particularly alarming, as it often signals the systemic spread of the infection and requires immediate medical attention. Early recognition of this rash is critical for prompt intervention to prevent severe outcomes, as meningococcal disease can progress rapidly and lead to septic shock or death.

While severe headache, high fever, and abdominal pain can also present in cases of meningococcal infection, the distinctive purplish rash is a hallmark sign that differentiates it from other infections and emphasizes the need for urgent evaluation and treatment.